Topic: Algorithms

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Theseus: Fast and Optimal Affine-Gap Sequence-to-Graph Alignment
Paper • Feb 14, 2026 • bioRxiv • Albert Jimenez-Blanco, et al.
Sequence-to-graph alignment is a cornerstone of modern pangenomics, yet current optimal algorithms suffer from high memory and computational costs. We present Theseus, a novel, fast, and optimal af...

Topic: Algorithms

Short answer

Theseus: Fast and Optimal Affine-Gap Sequence-to-Graph Alignment

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