This page shows the most relevant public items for Structural Biology, ranked by trend activity and review signal. Use weekly for fast changes, monthly for more stable patterns, and all-time for evergreen picks.
Paper • Jul 15, 2021 • Nature • John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Demis Hassabis
Proteins are essential to life, and understanding their structure can facilitate a mechanistic understanding of their function. We provide the first computational method that can regularly predict ...
Paper • Oct 4, 2021 • bioRxiv • Richard Evans, Michael O'Neill, Alexander Pritzel, Natasha Antropova, Andrew Senior, Tim Green, Augustin Žídek, Russ Bates, Sam Blackwell, Jason Yim, Olaf Ronneberger, Sebastian Bodenstein, Michal Zielinski, Alex Bridgland, Anna Potapenko, Andrew Cowie, Kathryn Tunyasuvunakool, Rishub Jain, Ellen Clancy, Pushmeet Kohli, John Jumper, Demis Hassabis
While AlphaFold 2 achieved unprecedented accuracy in predicting the structure of single protein chains, biological functions are primarily carried out by multi-protein complexes. We present AlphaFo...
Paper • Feb 19, 2026 • bioRxiv • M. Zeng, R. Ragoza, T. Jumper
While tools like AlphaFold have mastered the 20 canonical amino acids, expanding structural prediction to include noncanonical amino acids (NCAAs) remains a manual, computationally intensive proces...
Paper • Feb 23, 2026 • bioRxiv • Liu Chuanyang, Jiyuan Liu, Xinyuan Qiu, Xiaomin Wu, Wenying Li, Lu Min, Guohao Zhang, Shaowei Zhang, Lingyun Zhu
The paper explores how universal physical laws dictate the folding and assembly of proteins, challenging the stochastic views of structural formation. The authors argue that protein genesis follows...
Paper • Feb 17, 2026 • bioRxiv • Thomas Muentener, Dylan Abramson, Sebastian Hiller
The structural characterization of the vast protein universe is currently limited by the throughput of experimental methods. While AlphaFold has revolutionized structural prediction, experimental v...
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